Inhibitory actions of selected natural substances on formation of advanced glycation endproducts and advanced oxidation protein products

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Inhibitory actions of selected natural substances on formation of advanced glycation endproducts and advanced oxidation protein products

BACKGROUND Advanced glycation endproducts (AGE) and advanced oxidation protein products (AOPP) arise as a result of excessive glycation and oxidation processes of proteins in hyperglycemia and oxidative stress conditions respectively, both in vivo and in vitro. In vivo these processes are especially intensified in patients with diabetes, and the adverse effects of AGE and AOPP are particularly ...

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The Tibetan herbal medicines Padma 28 and Padma Circosan inhibit the formation of advanced glycation endproducts (AGE) and advanced oxidation protein products (AOPP) in vitro

BACKGROUND Advanced glycation endproducts (AGE) and advanced oxidation protein products (AOPP) play a pivotal role in the development of diabetes associated diseases. The herbal medicines Padma 28 and Padma Circosan have shown effectiveness in symptoms of diabetes associated diseases and have antioxidant effects. It is not known whether inhibition of AGE and AOPP formation is a mechanism of the...

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Advanced glycation end-products and advanced oxidation protein products in patients with diabetes mellitus.

Accelerated glycoxidation takes part in the development of diabetic complications. We determined advanced glycation end-products (AGEs) and advanced oxidation protein products (AOPP) in the sera of 52 patients with diabetes mellitus (DM) - 18 with DM Type 1 and 34 with DM Type 2 and examined their relationship to the compensation of the disease. AGEs were estimated spectrofluorimetrically (350 ...

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Salvia reuterana Extract Prevents Formation of Advanced Glycation End Products: An In Vitro Study

       In this study, we examined the antioxidant activities of methanolic extract of three endemic species of Salvia from Iran (S. lachno...

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Novel inhibitors of advanced glycation endproducts.

Enhanced formation and accumulation of advanced glycation endproducts (AGE's) have been proposed to play a major role in the pathogenesis of diabetic complications, aging, atherosclerosis, and Alzheimer disease leading to progressive and irreversible intermolecular protein crosslinkings. This process is accelerated in diabetes and has been postulated to contribute to the development of a range ...

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ژورنال

عنوان ژورنال: BMC Complementary and Alternative Medicine

سال: 2016

ISSN: 1472-6882

DOI: 10.1186/s12906-016-1353-0